The mimetic of the brain neurotrophic factor GSB-106 has neuroprotective and neuroregenerative effects in experimental ischemic stroke

• मुख्य लेखकों: P. Yu. Povarnina (लेखक), T. A. Antipova (लेखक), I. O. Logvinov (लेखक), D. M. Nikiforov (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: LLC "Publisher OKI", 2022-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background. A dimeric dipeptide mimetic of the brain-derived neurotrophic factor loop 4, bis(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide (GSB-106), which activates TrkB, PI3K/AKT, MAPK/ERK and PLC-γ1 was created at the V. V. Zakusov Research Institute of Pharmacology. GSB-106 showed neurop...