The mimetic of the brain neurotrophic factor GSB-106 has neuroprotective and neuroregenerative effects in experimental ischemic stroke

• প্রধান লেখক: P. Yu. Povarnina (Author), T. A. Antipova (Author), I. O. Logvinov (Author), D. M. Nikiforov (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: LLC "Publisher OKI", 2022-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background. A dimeric dipeptide mimetic of the brain-derived neurotrophic factor loop 4, bis(N-monosuccinyl-L-seryl-L-lysine) hexamethylenediamide (GSB-106), which activates TrkB, PI3K/AKT, MAPK/ERK and PLC-γ1 was created at the V. V. Zakusov Research Institute of Pharmacology. GSB-106 showed neurop...