KIF20A is associated with clinical prognosis and synergistic effect of gemcitabine combined with ferroptosis inducer in lung adenocarcinoma

• Main Authors: Hua He (Author), Lu Liang (Author), Jingjing Huang (Author), Shiyao Jiang (Author), Yueying Liu (Author), Xiaoyan Sun (Author), Yi Li (Author), Li Cong (Author), Yiqun Jiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gemcitabine (GEM), an antimetabolite that terminates DNA synthesis, is commonly used in the treatment of cancers including lung adenocarcinoma (LUAD). However, downregulation of sensitivity limits the therapeutic effect. Ferroptosis as the new form of regulated cell death has been shown to have grea...