Activation of Protease-Activated Receptor 2-Mediated Signaling by Mast Cell Tryptase Modulates Cytokine Production in Primary Cultured Astrocytes

Protease-activated receptor 2 (PAR-2), which is abundantly expressed in astrocytes, is known to play major roles in brain inflammation. However, the influence of the natural agonist of PAR-2, tryptase, on proinflammatory mediator releasedfrom astrocytes remains uninvestigated. In the present study,...

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Main Authors: Xiaoning Zeng (Author), Shu Zhang (Author), Luwei Xu (Author), Haiwei Yang (Author), Shaoheng He (Author)
Format: Book
Published: Hindawi Limited, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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