Molecular recognition requires dimerization of a VHH antibody

• Autores principales: Christopher A. Smith (Autor), Gregory J. Sonneson (Autor), Robert J. Hoey (Autor), Jennifer M. Hinerman (Autor), Kimberly Sheehy (Autor), Richard Walter (Autor), Andrew B. Herr (Autor), James R. Horn (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

ABSTRACTCamelid heavy-chain-only antibodies are a unique class of antibody that possesses only a single variable domain (termed VHH) for antigen recognition. Despite their apparent canonical mechanism of target recognition, where a single VHH domain binds a single target, an anti-caffeine VHH has be...