Biphasic Medium Using Nicotinamide for Detection of Pyrazinamide Resistance in <i>Mycobacterium tuberculosis</i>

• Main Authors: Waraporn Thuansuwan (Author), Charoen Chuchottaworn (Author), Chie Nakajima (Author), Yasuhiko Suzuki (Author), Nuntaree Chaichanawongsaroj (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reliable drug susceptibility testing of pyrazinamide (PZA) is technically difficult, since PZA activity is pH sensitive. The aim of this study was to evaluate a biphasic medium assay (BMA) for the reliable detection of PZA resistance in <i>Mycobacterium tuberculosis</i> (MTB) using nicot...