Pleiotropic effects of glitazones: a double edge sword?
Glitazones (thiazolidinediones) are drugs used for diabetes mellitus type 2. By binding to Peroxisome Proliferator-Activated Receptor γ (PPARγ) they modulate transcription of genes of carbohydrate and lipid metabolism. Through PPARγ stimulation, however, glitazones also affect other genes, encompass...
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| Format: | Book |
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Frontiers Media S.A.,
2011-03-01T00:00:00Z.
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A1234.567 |
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