Physical Factors Affecting Plasmid DNA Compaction in Stearylamine-Containing Nanoemulsions Intended for Gene Delivery

• Главные авторы: Eryvaldo Socrates Tabosa do Egito (Автор), Francisco Alexandrino (Автор), Lourena Mafra Verissimo (Автор), Lucymara Fassarella Agnez-Lima (Автор), Lucila Carmem Monte Egito (Автор), André Leandro Silva (Автор), Anselmo Gomes de Oliveira (Автор)
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• Опубликовано: MDPI AG, 2012-06-01T00:00:00Z.
• Предметы: article
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Cationic lipids have been used in the development of non-viral gene delivery systems as lipoplexes. Stearylamine, a cationic lipid that presents a primary amine group when in solution, is able to compact genetic material by electrostatic interactions. In dispersed systems such as nanoemulsions this...