In Vivo Monitoring of the Antiangiogenic Effect of Neurotensin Receptor-Mediated Radiotherapy by Small-Animal Positron Emission Tomography: A Pilot Study

• Main Authors: Simone Maschauer (Author), Tina Ruckdeschel (Author), Philipp Tripal (Author), Roland Haubner (Author), Jürgen Einsiedel (Author), Harald Hübner (Author), Peter Gmeiner (Author), Torsten Kuwert (Author), Olaf Prante (Author)
• Format: Book
• Published: MDPI AG, 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The neurotensin receptor (NTS1) has emerged as an interesting target for molecular imaging and radiotherapy of NTS-positive tumors due to the overexpression in a range of tumors. The aim of this study was to develop a 177Lu-labeled NTS1 radioligand, its application for radiotherapy in a preclinical...