A class of carbonic anhydrase IX/XII - selective carboxylate inhibitors
A small series of 2,4-dioxothiazolidinyl acetic acids was prepared from thiourea, chloroacetic acid, aromatic aldehydes, and ethyl-2-bromoacetate. They were assayed for the inhibition of four physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isoforms of human (h) origin, the cytosolic hCA...
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Main Authors: | , , , , |
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Format: | Book |
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Taylor & Francis Group,
2020-01-01T00:00:00Z.
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A1234.567 |
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