Epithelial immunomodulation by aerosolized Toll-like receptor agonists prevents allergic inflammation in airway mucosa in mice

• Main Authors: David L. Goldblatt (Author), Gabriella Valverde Ha (Author), Shradha Wali (Author), Vikram V. Kulkarni (Author), Michael K. Longmire (Author), Ana M. Jaramillo (Author), Rosha P. Chittuluru (Author), Adrienne Fouts (Author), Margarita Martinez-Moczygemba (Author), Jonathan T. Lei (Author), David P. Huston (Author), Michael J. Tuvim (Author), Burton F. Dickey (Author), Scott E. Evans (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Allergic asthma is a chronic inflammatory respiratory disease associated with eosinophilic infiltration, increased mucus production, airway hyperresponsiveness, and airway remodeling. Epidemiologic data reveal that the prevalence of allergic sensitization and associated diseases has increased in the...