Experimental and Molecular Docking Studies of Cyclic Diphenyl Phosphonates as DNA Gyrase Inhibitors for Fluoroquinolone-Resistant Pathogens

• Main Authors: Neveen M. Saleh (Author), Yasmine S. Moemen (Author), Sara H. Mohamed (Author), Ghady Fathy (Author), Abdullah A. S. Ahmed (Author), Ahmed A. Al-Ghamdi (Author), Sami Ullah (Author), Ibrahim El-Tantawy El Sayed (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DNA gyrase and topoisomerase IV are proven to be validated targets in the design of novel antibacterial drugs. In this study, we report the antibacterial evaluation and molecular docking studies of previously synthesized two series of cyclic diphenylphosphonates (<b>1a</b>-<b>e<...