Lipid Nanoparticles as a Shuttle for Anti-Adipogenic miRNAs to Human Adipocytes

• Main Authors: Anna-Laurence Sch (Author), Julia Fuchs (Author), Ivan Vidakovic (Author), Oliver Höller (Author), Gebhard Schratter (Author), Gunter Almer (Author), Eleonore Fröhlich (Author), Andreas Zimmer (Author), Martin Wabitsch (Author), Karin Kornmueller (Author), Ruth Prassl (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity and type 2 diabetes are major health burdens for which no effective therapy is available today. One treatment strategy could be to balance the metabolic functions of adipose tissue by regulating gene expressions using miRNAs. Here, we have loaded two anti-adipogenic miRNAs (miR26a and miR27a...