Figainin 1, a Novel Amphibian Skin Peptide with Antimicrobial and Antiproliferative Properties

• Main Authors: Carlos José Correia Santana (Author), Ana Carolina Martins Magalhães (Author), Agenor C. M. dos Santos Júnior (Author), Carlos André Ornelas Ricart (Author), Beatriz D. Lima (Author), Alice da Cunha Morales Álvares (Author), Sonia Maria de Freitas (Author), Osmindo Rodrigues Pires (Author), Wagner Fontes (Author), Mariana S. Castro (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amphibian skin secretions are abundant in bioactive compounds, especially antimicrobial peptides. These molecules are generally cationic and rich in hydrophobic amino acids, have an amphipathic structure and adopt an α-helical conformation when in contact with microorganisms membranes. In this work,...