Redox Regulation of PTEN by Peroxiredoxins

• Main Authors: Thang Nguyen Huu (Author), Jiyoung Park (Author), Ying Zhang (Author), Iha Park (Author), Hyun Joong Yoon (Author), Hyun Ae Woo (Author), Seung-Rock Lee (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phosphatase and tensin homolog deleted on chromosome 10 (<i>PTEN</i>) is known as a tumor suppressor gene that is frequently mutated in numerous human cancers and inherited syndromes. PTEN functions as a negative regulator of PI3K/Akt signaling pathway by dephosphorylating phosphatidylin...