A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes.
Myristoylation is a lipid modification involving the addition of a 14-carbon unsaturated fatty acid, myristic acid, to the N-terminal glycine of a subset of proteins, a modification that promotes their binding to cell membranes for varied biological functions. The process is catalyzed by myristoyl-C...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2014-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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