Norcantharidin down-regulates iron contents in the liver and spleen of lipopolysaccharide-treated mice

• Main Authors: Jie Zheng (Author), Jiao-Jiao Wang (Author), Hui-Min Ma (Author), Meng-Qi Shen (Author), Zhong-Ming Qian (Author), Yu-Xin Bao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective The inhibiting effect of Norcantharidin (NCTD) on IL-6 (interleukin-6) and STAT3 and the involvement of the IL-6/STAT3 pathway in hepcidin expression prompted us to speculate that NCTD could affect iron metabolism.Methods We examined the effects of NCTD on serum iron (SI) and transferrin (...