Reciprocal interference between the NRF2 and LPS signaling pathways on the immune‐metabolic phenotype of peritoneal macrophages

• Main Authors: Federica Mornata (Author), Giovanna Pepe (Author), Chiara Sfogliarini (Author), Electra Brunialti (Author), Gianenrico Rovati (Author), Massimo Locati (Author), Adriana Maggi (Author), Elisabetta Vegeto (Author)
• Format: Book
• Published: Wiley, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The metabolic and immune adaptation to extracellular signals allows macrophages to carry out specialized functions involved in immune protection and tissue homeostasis. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a transcription factor that coordinates cell redox and metabolic res...