Extracellular Ca2+ promotes nitric oxide production via Ca2+-sensing receptor-Gq/11 protein-endothelial nitric oxide synthase signaling in human vascular endothelial cells

• मुख्य लेखकों: Takahiro Horinouchi (लेखक), Yuichi Mazaki (लेखक), Koji Terada (लेखक), Soichi Miwa (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

This study examined the possible involvement of Ca2+-sensing receptor (CaSR) in nitric oxide (NO) production in human vascular endothelial cells. Extracellular Ca2+ elevated the intracellular Ca2+ concentration, the endothelial NO synthase (eNOS) phosphorylation level, and NO release from the cells....