Extracellular Ca2+ promotes nitric oxide production via Ca2+-sensing receptor-Gq/11 protein-endothelial nitric oxide synthase signaling in human vascular endothelial cells

• Main Authors: Takahiro Horinouchi (Author), Yuichi Mazaki (Author), Koji Terada (Author), Soichi Miwa (Author)
• 格式: 圖書
• 出版: Elsevier, 2020-08-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

This study examined the possible involvement of Ca2+-sensing receptor (CaSR) in nitric oxide (NO) production in human vascular endothelial cells. Extracellular Ca2+ elevated the intracellular Ca2+ concentration, the endothelial NO synthase (eNOS) phosphorylation level, and NO release from the cells....