Improvement of gut-vascular barrier by terlipressin reduces bacterial translocation and remote organ injuries in gut-derived sepsis

• Main Authors: Zenan Chang (Author), Yinan Zhang (Author), Ming Lin (Author), Shihong Wen (Author), Hanjin Lai (Author), Yaqing Zhan (Author), Xiufen Zhu (Author), Zhikun Huang (Author), Xuyu Zhang (Author), Zimeng Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gut-vascular barrier (GVB) serves as the last barrier to limit the migration of intestinal toxins into the blood circulation. The efficacy of terlipressin (a vasopressin V1 receptor agonist) in reducing GVB and multiple organ damage in gut-derived sepsis is unknown. In this study, we hypothesized th...