Antihypertensive effect of piperitenone oxide on spontaneously hypertensive rat by regulating calcium balance and reducing endothelin-1 secretion

• Glavni autori: Wei Lan (Autor), Hong Ping Zhang (Autor), Ying Wang (Autor), Min Jiang (Autor), Qian Li (Autor), Dongqing An (Autor)
• Format: Knjiga
• Izdano: Bangladesh Pharmacological Society, 2017-09-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The purpose of this study was to investigate the antihypertensive mecha-nisms of piperitenone oxide in spontaneously hypertensive rat (SHR). Compared to control SHR, piperitenone oxide reduced the systolic blood pressure and serum endothelium-1 (ET-1). The nitric oxide (NO) production and ET-1 secre...