Dramatic Suppression of Lipogenesis and No Increase in Beta-Oxidation Gene Expression Are among the Key Effects of Bergamot Flavonoids in Fatty Liver Disease

• Main Authors: Maddalena Parafati (Author), Daniele La Russa (Author), Antonella Lascala (Author), Francesco Crupi (Author), Concetta Riillo (Author), Bartosz Fotschki (Author), Vincenzo Mollace (Author), Elzbieta Janda (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bergamot flavonoids have been shown to prevent metabolic syndrome, non-alcoholic fatty liver disease (NAFLD) and stimulate autophagy in animal models and patients. To investigate further the mechanism of polyphenol-dependent effects, we performed a RT2-PCR array analysis on 168 metabolism, transport...