Microsatellite instability in endometrial cancer: the role of diagnostic methods and their clinical application. Expert consensus

• Main Authors: A. S. Tyulyandina (Author), E. A. Ulrikh (Author), L. A. Kolomiets (Author), S. E. Krasilnikov (Author), A. G. Kedrova (Author), A. A. Rumyantsev (Author), G. A. Raskin (Author), A. I. Nesterova (Author), M. V. Volkonskiy (Author), O. N. Churuksaeva (Author), A. Yu. Goryainova (Author), V. V. Zhavoronkova (Author), V. N. Dmitriev (Author), S. T. Nazranova (Author), A. V. Shkradyuk (Author), K. S. Volkova (Author), A. I. Arutyunova (Author), S. N. Kunitskaya (Author), L. V. Stepura (Author), T. G. Zolotoreva (Author), E. B. Shakhnovich (Author), E. V. Ponomareva (Author), M. A. Strokova (Author), A. S. Danilova (Author), E. S. Martynova (Author)
• Format: Book
• Published: ABV-press, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Deficient DNA mismatch repair (dMMR) is a rare molecular disorder found in 20-30 % of endometrial tumors. Laboratory identification of dMMR/microsatellite instability (MSI) has a high diagnostic value, since these impairments are considered as biomarkers of endometrial adenocarcinoma. They help to i...