Sodium Dichloroacetate Pharmacological Effect as Related to Na-K-2Cl Cotransporter Inhibition in Rats

• Autori principali: Jūratė Stanevičiūtė (Autore), Milda Juknevičienė (Autore), Jolita Palubinskienė (Autore), Ingrida Balnytė (Autore), Angelija Valančiūtė (Autore), Rūta Vosyliūtė (Autore), Kęstutis Sužiedėlis (Autore), Vaiva Lesauskaitė (Autore), Donatas Stakišaitis (Autore)
• Natura: Libro
• Pubblicazione: SAGE Publishing, 2018-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The study objective was to investigate a possible sodium dichloroacetate (DCA) pharmacological mechanism causing an increase in diuresis in rats. The aim was to define characteristics of 24-hour urinary Na + , K + , Cl − , Ca 2+ , and Mg 2+ excretion in Wistar male rats and to evaluate effect of a s...