NanoLuc luciferase - A multifunctional tool for high throughput antibody screening

• Main Authors: Nicolas eBoute (Author), Peter eLowe (Author), Sven eBerger (Author), Martine eMalissard (Author), Alain eRobert (Author), Michael eTesar (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Based on the recent development of NanoLuc Luciferase a small (19 kDa), highly stable, ATP independent, bioluminescent protein, an extremely robust and ultra high sensitivity screening system has been developed whereby primary hits of therapeutic antibodies and antibody fragments could be characteri...