MEK inhibitors - novel targeted therapies of neurofibromatosis associated benign and malignant lesions

Abstract MAP/ERK kinase 1 and 2 (MEK 1/2) inhibitors (MEKi) are investigated in several trials to treat lesions that arise from pathogenic variants of the Neurofibromatosis type 1 and type 2 genes (NF1, NF2). These trials showed that MEKi are capable to shrink volume of low grade gliomas and plexifo...

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Main Author: Anja Harder (Author)
Format: Book
Published: BMC, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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