Numerical and Machine Learning Analysis of the Parameters Affecting the Regionally Delivered Nasal Dose of Nano- and Micro-Sized Aerosolized Drugs

• Main Authors: Ali Farnoud (Author), Hesam Tofighian (Author), Ingo Baumann (Author), Kaveh Ahookhosh (Author), Oveis Pourmehran (Author), Xinguang Cui (Author), Vincent Heuveline (Author), Chen Song (Author), Sarah Vreugde (Author), Peter-John Wormald (Author), Michael P. Menden (Author), Otmar Schmid (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The nasal epithelium is an important target for drug delivery to the nose and secondary organs such as the brain via the olfactory bulb. For both topical and brain delivery, the targeting of specific nasal regions such as the olfactory epithelium (brain) is essential, yet challenging. In this study,...