Oral Substitution of Melatonin in Critical Care: A Pharmacokinetic Study in Patients with Intracranial Hemorrhage

• Main Authors: Mohammadreza Rouini (Author), Niloofar Khoshnam Rad (Author), Mojtaba Mojtahedzadeh (Author), Atabak Najafi (Author), Hamidreza Sharifnia (Author), Mehrnoush Dianatkhah (Author), Farhad Najmeddin (Author), Ali Mohammad Hadi (Author), Bita Shahrami (Author)
• Format: Book
• Published: Research Center for Rational Use of Drugs (RCRUD), 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Intracranial hemorrhage (ICH) is a devastating condition with a high mortality and morbidity rate. Neuroprotective agents protect surrounding brain tissue from the toxic effects of hematoma and can result in better outcomes. There is evidence demonstrating the neuroprotective benefits of...