Nanoencapsulation as a General Solution for Lyophilization of Labile Substrates

• Main Authors: Girish Vallerinteavide Mavelli (Author), Samira Sadeghi (Author), Siddhesh Sujit Vaidya (Author), Shik Nie Kong (Author), Chester Lee Drum (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein macromolecules occur naturally at the nanoscale. The use of a dedicated nanoparticle as a lyophilization excipient, however, has not been reported. Because biopolymeric and lipid nanoparticles often denature protein macromolecules and commonly lack the structural rigidity to survive the free...