Enhanced Oral Bioavailability, Anti-Tumor Activity and Hepatoprotective Effect of 6-Shogaol Loaded in a Type of Novel Micelles of Polyethylene Glycol and Linoleic Acid Conjugate

• Príomhchruthaitheoirí: Huiyun Zhang (Údar), Qilong Wang (Údar), Congyong Sun (Údar), Yuan Zhu (Údar), Qiuxuan Yang (Údar), Qiuyu Wei (Údar), Jiaxin Chen (Údar), Wenwen Deng (Údar), Michael Adu-Frimpong (Údar), Jiangnan Yu (Údar), Ximing Xu (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2019-03-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

：6-shogaol is a promising anti-cancer and anti-inflammatory agent. However, the treatment effectiveness of 6-shogaol is limited by poor water solubility, poor oral absorption and rapid metabolism. Herein, 6-shogaol loaded in micelles (SMs) were designed to improve 6-shogaol’s solubility and bioavail...