Cell Cycle Modulation of CHO-K1 Cells Under Genistein Treatment Correlates with Cells Senescence, Apoptosis and ROS Level but in a Dose-Dependent Manner

• Main Authors: Riris Istighfari Jenie (Author), Nur Dina Amalina (Author), Gagas Pradani Nur Ilmawati (Author), Rohmad Yudi Utomo (Author), Muthi Ikawati (Author), Annisa Khumaira (Author), Jun- Ya Kato (Author), Edy Meiyanto (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Genistein, a soy isoflavone, exhibits a biphasic effect on cells proliferation with some different effects between ER-alpha and ER-beta. The objective of this present study is to determine the modulatory effect based on cell cycle progression under genistein treatment in combination with 17...