Modelling Anti-Ov16 IgG4 Antibody Prevalence as an Indicator for Evaluation and Decision Making in Onchocerciasis Elimination Programmes.

• Main Authors: Yvonne L Lont (Author), Luc E Coffeng (Author), Sake J de Vlas (Author), Allison Golden (Author), Tala de Los Santos (Author), Gonzalo J Domingo (Author), Wilma A Stolk (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Onchocerciasis is targeted for elimination in Africa through annual or biannual ivermectin mass drug administration (MDA). An immunodiagnostic test, based on the detection of human IgG4 antibodies in the blood to the Onchocerca volvulus-specific antigen Ov16, is one of the recommended too...