Mechanisms involved in follistatin‐induced hypertrophy and increased insulin action in skeletal muscle

• Main Authors: Xiuqing Han (Author), Lisbeth Liliendal Valbjørn Møller (Author), Estelle De Groote (Author), Kirstine Nyvold Bojsen‐Møller (Author), Jonathan Davey (Author), Carlos Henríquez‐Olguin (Author), Zhencheng Li (Author), Jonas Roland Knudsen (Author), Thomas Elbenhardt Jensen (Author), Sten Madsbad (Author), Paul Gregorevic (Author), Erik Arne Richter (Author), Lykke Sylow (Author)
• Format: Book
• Published: Wiley, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skeletal muscle wasting is often associated with insulin resistance. A major regulator of muscle mass is the transforming growth factor β (TGF‐β) superfamily, including activin A, which causes atrophy. TGF‐β superfamily ligands also negatively regulate insulin‐sensitive proteins,...