The Nanotechnology-Based Approaches against Kirsten Rat Sarcoma-Mutated Cancers

• Main Authors: Fernanda Andrade (Author), Júlia German-Cortés (Author), Sara Montero (Author), Pilar Carcavilla (Author), Diego Baranda-Ma (Author), Marc Moltó-Abad (Author), Joaquín Seras-Franzoso (Author), Zamira Vanessa Díaz-Riascos (Author), Diana Rafael (Author), Ibane Abasolo (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Kirsten rat sarcoma (KRAS) is a small GTPase which acts as a molecular switch to regulate several cell biological processes including cell survival, proliferation, and differentiation. Alterations in KRAS have been found in 25% of all human cancers, with pancreatic cancer (90%), colorectal cancer (4...