Genetic Attenuation of Paraoxonase 1 Activity Induces Proatherogenic Changes in Plasma Proteomes of Mice and Humans

• Main Authors: Marta Sikora (Author), Ewa Bretes (Author), Joanna Perła-Kaján (Author), Izabela Lewandowska (Author), Łukasz Marczak (Author), Hieronim Jakubowski (Author)
• 格式: 圖書
• 出版: MDPI AG, 2020-11-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

High-density lipoprotein (HDL), in addition to promoting reverse cholesterol transport, possesses anti-inflammatory, antioxidative, and antithrombotic activities. Paraoxonase 1 (PON1), carried on HDL in the blood, can contribute to these antiatherogenic activities. The <i>PON1</i>-<i&...