Valproate, risperidone, and paliperidone: A case of valproate-induced hyperammonemic encephalopathy

• Main Authors: Kyle Wesselman, PharmD candidate, MA, BS (Author), Vincent Cavaliere, PharmD, MM, BCPP (Author), Rakesh Goyal, MD (Author), Eric Anderson, MD, MBA, FAPA (Author)
• Format: Book
• Published: American Association of Psychiatric Pharmacists, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyperammonemia is a well-known adverse effect of valproate that can progress to a potentially fatal condition known as valproate-induced hyperammonemic encephalopathy (VHE). VHE is more common when valproate is used in combination therapy with other antiepileptic medications. A growing number of cas...