A Biosimilarity Study Between QX001S and Ustekinumab in Healthy Chinese Male Subjects

• Main Authors: Lei Gao (Author), Qingmei Li (Author), Hong Zhang (Author), Min Wu (Author), Min Fang (Author), Lizhi Yang (Author), Xiaojiao Li (Author), Jingrui Liu (Author), Cuiyun Li (Author), Hong Chen (Author), Xiaoxue Zhu (Author), Yanhua Ding (Author), Mingwei Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To evaluate the tolerance, variability, and pharmacokinetics (PK) of QX001S, a biosimilar for ustekinumab, in healthy Chinese men.Methods: One hundred and seventy-eight healthy men were recruited in this randomized, double-blind, single-dose, two-arm, parallel study, and received 45 mg of...