Exploring the link between pyrethroids exposure and dopaminergic degeneration through morphometric, immunofluorescence, and in-silico approaches: the therapeutic role of chitosan-encapsulated curcumin nanoparticles

• Main Authors: Badriyah S. Alotaibi (Author), Amany Abdel-Rahman Mohamed (Author), Yasmina M. Abd-Elhakim (Author), Ahmed E. Noreldin (Author), Moustafa Elhamouly (Author), Tarek Khamis (Author), Ali H. El-Far (Author), Manal E. Alosaimi (Author), Naief Dahran (Author), Leena S. Alqahtani (Author), Mario Nicotra (Author), Mohamed El-Gamal (Author), Alessandro Di Cerbo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The synthetic pyrethroid derivative fenpropathrin (FNE), a commonly used insecticide, has been associated with various toxic effects in mammals, particularly neurotoxicity. The study addressed the hallmarks of the pathophysiology of Parkinson's disease upon oral exposure to fenpro...