Impact of the Endocannabinoid System on Bone Formation and Remodeling in p62 KO Mice

• Autors principals: Christina Keller (Autor), Timur Alexander Yorgan (Autor), Sebastian Rading (Autor), Thorsten Schinke (Autor), Meliha Karsak (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Several studies have shown that the G-protein coupled cannabinoid receptor CB2 and its interaction partner p62 are molecularly involved in bone remodeling processes. Pharmacological activation of the CB2 receptor enhanced bone volume in postmenopausal osteoporosis and arthritis models in rodents, wh...