Seatbelts in CAR therapy: How Safe Are CARS?
T-cells genetically redirected with a chimeric antigen receptor (CAR) to recognize tumor antigens and kill tumor cells have been infused in several phase 1 clinical trials with success. Due to safety concerns related to on-target/off-tumor effects or cytokine release syndrome, however, strategies to...
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Format: | Book |
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MDPI AG,
2015-05-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |