Design of Effective Primary MicroRNA Mimics With Different Basal Stem Conformations

Primary microRNA (pri-miRNA) mimics are important mediators of effective gene silencing and are well suited for sustained therapeutic applications. Pri-miRNA mimics are processed in the endogenous miRNA biogenesis pathway, where elements of the secondary RNA structure are crucial for efficient miRNA...

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Main Authors: Fiona T van den Berg (Author), John J Rossi (Author), Patrick Arbuthnot (Author), Marc S Weinberg (Author)
Format: Book
Published: Elsevier, 2016-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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