Neuronal and glial characterization in the rostrocaudal axis of the human anterior olfactory nucleus: Involvement in Parkinson's disease

• Main Authors: Sandra Villar-Conde (Author), Veronica Astillero-Lopez (Author), Melania Gonzalez-Rodriguez (Author), Daniel Saiz-Sanchez (Author), Isabel Ubeda-Banon (Author), Alicia Flores-Cuadrado (Author), Alino Martinez-Marcos (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyposmia is one of the prodromal symptoms of Parkinson's disease (PD) and a red flag in clinical diagnosis. Neuropathologically, this sign correlates with α-synuclein involvement in the anterior olfactory nucleus (AON). Neurodegeneration, microgliosis, and astrogliosis in AON are poorly studied...