Falcarindiol Purified From Carrots Leads to Elevated Levels of Lipid Droplets and Upregulation of Peroxisome Proliferator-Activated Receptor-γ Gene Expression in Cellular Models

• Main Authors: Camilla Bertel Andersen (Author), Anders Runge Walther (Author), Emma Pipó-Ollé (Author), Martine K. Notabi (Author), Sebastian Juul (Author), Mathias Hessellund Eriksen (Author), Adam Leslie Lovatt (Author), Richard Cowie (Author), Jes Linnet (Author), Morten Kobaek-Larsen (Author), Rime El-Houri (Author), Morten Østergaard Andersen (Author), Martin Aage Barsøe Hedegaard (Author), Lars Porskjær Christensen (Author), Eva Christensen Arnspang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Falcarindiol (FaDOH) is a cytotoxic and anti-inflammatory polyacetylenic oxylipin found in food plants of the carrot family (Apiaceae). FaDOH has been shown to activate PPARγ and to increase the expression of the cholesterol transporter ABCA1 in cells, both of which play an important role in lipid m...