The Addition of Manganese Porphyrins during Radiation Inhibits Prostate Cancer Growth and Simultaneously Protects Normal Prostate Tissue from Radiation Damage

• Main Authors: Arpita Chatterjee (Author), Yuxiang Zhu (Author), Qiang Tong (Author), Elizabeth A. Kosmacek (Author), Eliezer Z. Lichter (Author), Rebecca E. Oberley-Deegan (Author)
• Format: Book
• Published: MDPI AG, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiation therapy is commonly used for prostate cancer treatment; however, normal tissues can be damaged from the reactive oxygen species (ROS) produced by radiation. In separate reports, we and others have shown that manganese porphyrins (MnPs), ROS scavengers, protect normal cells from radiation-i...