Pharmacokinetic-Pharmacodynamic Modeling of Midazolam in Pediatric Surgery

• Main Authors: Carmen Flores-Pérez (Author), Luis Alfonso Moreno-Rocha (Author), Juan Luis Chávez-Pacheco (Author), Norma Angélica Noguez-Méndez (Author), Janett Flores-Pérez (Author), Delfina Ortiz-Marmolejo (Author), Lina Andrea Sarmiento-Argüello (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Midazolam (MDZ) is used for sedation in surgical procedures; its clinical effect is related to its receptor affinity and the dose administered. Therefore, a pharmacokinetic-pharmacodynamic (PK-PD) population model of MDZ in pediatric patients undergoing minor surgery is proposed. A descriptive, obse...