Inhibition of EGF and CoCl2-Induced HIF-1α and VEGF Production in Triple Negative MDA-MB-468 Cells by Umbelliprenin: Unveiling the Role of PI3K/AKT/mTOR and MAPK Pathways

Inhibition of EGF and CoCl2-Induced HIF-1α and VEGF Production in Triple Negative MDA-MB-468 Cells by Umbelliprenin: Unveiling the Role of PI3K/AKT/mTOR and MAPK Pathways

Background and objectives: Triple-negative breast cancer is a significant global health challenge, and there's growing interest in targeting multiple pathways for treatment. Umbelliprenin, derived from herbal sources, has shown anti-tumor potential. This study aimed to assess umbelliprenin'...

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Main Authors: Roya Atabakhshian (Author), Melina Moshirpour (Author), Mohammad Hadi Farjoo (Author), Shiva Ghafghazi (Author), Seyed Ali Ziai* (Author)
Format: Book
Published: Iranian Society of Pharmacognosy, 2024-01-01T00:00:00Z.
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