The association of ACTN3 R577X polymorphism with sports specificity in Japanese elite athletes

• Main Authors: Nobuhiko Akazawa (Author), Nao Ohiwa (Author), Kazuhiro Shimizu (Author), Natsumi Suzuki (Author), Hiroshi Kumagai (Author), Noriyuki Fuku (Author), Yasuhiro Suzuki (Author)
• Format: Book
• Published: Termedia Publishing House, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The α-actinin-3 proteins regulate muscle function and are located in the Z-line of the fast skeletal muscle. A common null polymorphism of R577X in α-actinin-3 gene (ACTN3) results in its complete absence in fast-twitch muscles. The ACTN3 R577X polymorphism is associated with sprint/power performanc...