Self-assembled PEGylated albumin nanoparticles (SPAN) as a platform for cancer chemotherapy and imaging

• Main Authors: Jung Eun Lee (Author), Myung Goo Kim (Author), Yeon Lim Jang (Author), Min Sang Lee (Author), Nak Won Kim (Author), Yue Yin (Author), Jong Han Lee (Author), Su Yeon Lim (Author), Ji Won Park (Author), Jaeyun Kim (Author), Doo Sung Lee (Author), Sun Hwa Kim (Author), Ji Hoon Jeong (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Paclitaxel (PTX) is used as a major antitumor agent for the treatment of recurrent and metastatic breast cancer. For the clinical application of PTX, it needs to be dissolved in an oil/detergent-based solvent due to its poor solubility in an aqueous medium. However, the formulation often causes unde...