Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

• Main Authors: Reisman SA (Author), Gahir SS (Author), Lee CY (Author), Proksch JW (Author), Sakamoto M (Author), Ward KW (Author)
• Format: Book
• Published: Dove Medical Press, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scott A Reisman, Sarabjit S Gahir, Chun-Yue I Lee, Joel W Proksch, Mitsumasa Sakamoto, Keith W Ward Reata Pharmaceuticals, Inc., Irving, TX 75063, USA Background: Omaveloxolone is a synthetic oleanane triterpenoid that pharmacologically activates Nrf2, a master transcription factor that regulates ge...