Pharmacokinetics and pharmacodynamics of the novel Nrf2 activator omaveloxolone in primates

Scott A Reisman, Sarabjit S Gahir, Chun-Yue I Lee, Joel W Proksch, Mitsumasa Sakamoto, Keith W Ward Reata Pharmaceuticals, Inc., Irving, TX 75063, USA Background: Omaveloxolone is a synthetic oleanane triterpenoid that pharmacologically activates Nrf2, a master transcription factor that regulates ge...

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Prif Awduron: Reisman SA (Awdur), Gahir SS (Awdur), Lee CY (Awdur), Proksch JW (Awdur), Sakamoto M (Awdur), Ward KW (Awdur)
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Cyhoeddwyd: Dove Medical Press, 2019-04-01T00:00:00Z.
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