Mildly Increased Renin Expression in the Absence of Kidney Injury in the Murine Transverse Aortic Constriction Model

• Main Authors: Marian Wesseling (Author), Eva Mulder (Author), Maike A. D. Brans (Author), Daniek. M. C. Kapteijn (Author), Marian Bulthuis (Author), Gerard Pasterkamp (Author), Marianne C. Verhaar (Author), A. H. Jan Danser (Author), Harry van Goor (Author), Jaap A. Joles (Author), Saskia C. A. de Jager (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiorenal syndrome type 2 is characterized by kidney failure as a consequence of heart failure that affects >50% of heart failure patients. Murine transverse aortic constriction (TAC) is a heart failure model, where pressure overload is induced on the heart without any systemic hypertension or...